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KMID : 0363219740120030183
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Korean Journal of Dermatology
1974 Volume.12 No. 3 p.183 ~ p.186
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Porphyria Cutanea Tarda-Report of a Case
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金淳宅/Kim, Soon Taek
成好錫/鄭泰安/Seong, Hou Suk/Chung, Tae An
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Abstract
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A case of porphyria cutanea tarda is reported, in which the photosensitive cutaneous symptoms developed in association with impaired hepatic function possibly related to chronic consumption of alcohol. Wood´s light examination of the urine revealed cowl red fluorescence, and qualitative chemical urinalysis was strong positive for uroporphy.´in and coproporphyrin. Biopsy of the skin showed subepidermal bulla with festooning arrangement of the naked papillae and basophilic degeneration of the dermis. The patient´s favorable response to alkalinization therapy by sodium bicarbonate per os is encouraging, even for a short period´s observation.
Clinical, histopathological, and biochemical features of this disease are also discussed.
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